Analisis Survival Pasien Kanker Paru-Paru Menggunakan Model Kaplan-Meier dan Regresi Cox Proportional Hazard

Langi, Isabel Desteny Queen (2026) Analisis Survival Pasien Kanker Paru-Paru Menggunakan Model Kaplan-Meier dan Regresi Cox Proportional Hazard. Bachelor thesis, Institut Teknologi Kalimantan.

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Abstract

Kanker paru-paru merupakan salah satu jenis kanker dengan angka kematian yang tinggi di dunia maupun di Indonesia. Tingginya angka mortalitas serta adanya data tersensor dalam pengamatan pasien menyebabkan analisis survival menjadi metode yang tepat untuk digunakan. Penelitian ini bertujuan untuk mengetahui gambaran ketahanan hidup pasien kanker paru-paru serta mengidentifikasi faktor-faktor yang mempengaruhi survival time pasien di RSUD Dr. Kanujoso Djatiwibowo menggunakan metode Kaplan-Meier dan regresi Cox Proportional Hazard. Variabel yang dianalisis meliputi jenis kelamin, kategori usia, stadium kanker, metastase, komorbid, dan riwayat merokok. Metode Kaplan-Meier digunakan untuk mengestimasi fungsi survival dan menggambarkan pola ketahanan hidup pasien, sedangkan regresi Cox Proportional Hazard digunakan untuk menganalisis faktor-faktor yang mempengaruhi risiko kematian. Hasil analisis Kaplan-Meier menunjukkan bahwa median survival time pasien kanker paru-paru adalah 200 hari dan probabilitas survival menurun seiring bertambahnya waktu pengamatan. Hasil uji Log-Rank menunjukkan bahwa variabel metastase (p-value = 0,008372) dan komorbid (p-value = 0,023562) memiliki perbedaan fungsi survival yang signifikan antar kelompok. Selanjutnya, hasil regresi Cox Proportional Hazard menunjukkan bahwa hanya variabel metastase yang berpengaruh signifikan terhadap survival time pasien kanker paru-paru (p-value = 0,023891). Berdasarkan model akhir yang diperoleh, pasien yang mengalami metastase memiliki risiko kematian sebesar 3,210184 kali lebih tinggi dibandingkan pasien yang tidak mengalami metastase. Dengan demikian, metastase merupakan faktor yang paling berpengaruh terhadap ketahanan hidup pasien kanker paru-paru pada penelitian ini.

Item Type: Thesis (Bachelor)
Subjects: A General Works > AI Indexes (General)
Divisions: Jurusan Matematika dan Teknologi Informasi > Ilmu Aktuaria
Depositing User: Isabel Desteny Queen Langi
Date Deposited: 17 Jul 2026 05:54
Last Modified: 17 Jul 2026 05:54
URI: http://repository.itk.ac.id/id/eprint/27001

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